The laboratory of Dr. Dr. Steven S. Welc, within the Department of Anatomy, Cell Biology & Physiology and Center for Musculoskeletal Health at the Indiana University School of Medicine, is seeking a highly motivated postdoctoral to study the pathophysiological mechanisms of skeletal and cardiac muscle adaptation in conditions of aging, exercise and disease. Our ongoing NIH-funded research includes investigations into the regulatory effects of fibroblasts on cardiac myocytes in Duchenne muscular dystrophy. The laboratory uses state-of-the-art technologies and tissue-specific mutant mouse models to examine the molecular mechanisms that underlie dystrophin-deficient cardiac remodeling. The project is collaborative and multidisciplinary with excellent opportunities for advanced training and scientific development.

The applicant must be highly self-motivated, able to design and conduct experiments independently, analyze and interpret results, read literature, present work at meetings, write scientific manuscripts, and speak and write fluently in English. Candidates should be able to function well independently and in a small group. US citizens or permanent residents will have the opportunity to compete for NIH-funded training grants, but this is not required.

The newly formed Indiana Center for Musculoskeletal Health (ICMH) is home to one of the largest bone and muscle research groups in the world, providing an exciting environment for collaborative musculoskeletal research with ample opportunities for trainees. To learn more about the ICMH: https://medicine.iu.edu/research/centers-institutes/musculoskeletal-health/

As the nation's largest medical school, IUSM is committed to being an institution that not only reflects the diversity of the learners we teach and the patient populations we serve, but also pursues the values of diversity, equity and inclusion that inform academic excellence. We desire candidates who enhance our representational diversity, as well as those whose work contributes to equitable and inclusive learning and working environments for our students, staff, and faculty. IUSM strives to take an anti-biased stance, regularly evaluating and updating its policies, procedures, and practices to confer equitable opportunities for contribution and advancement for all members of our community. We invite individuals who will join us in our mission to advance racial equity to transform health and wellbeing for all throughout the state of Indiana.

Indianapolis is the 12th largest city in the United States and is a thriving economic and cultural metropolis. The city and surrounding areas offer high quality of life with access to museums, cultural districts, excellent dining, professional sporting events, and historic sites. Residents enjoy low cost of living, safe neighborhoods, easy commutes, extensive recreational areas, and an award-winning international airport.

Doctorate or terminal degree required. Applicants must possess a PhD, MD, or MD/PhD degree and a strong background in biomedical research and preferably musculoskeletal or molecular biology. Prior work experience in transgenic and knockout mouse models, cardiac phenotyping, molecular and cell biology techniques, cell culture, biochemistry, histology, immunohistochemistry, immunofluorescence, genomics, proteomics and bioinformatics are highly desirable. 

Inquiries about this position should be sent to Dr. Welc: swelc@iu.edu